The Experience and Management of Medical Uncertainty in Telomere Biology Disorders
by Dr. Emily Pearce
The Telomere Biology Disorder community sends major congratulations to Dr. Emily Pearce for defending her dissertation and earning her PhD! Dr. Pearce’s thesis was titled “The Experience and Management of Medical Uncertainty in Telomere Biology Disorders” and...
Thymidine Nucleotide Metabolism Controls Human Telomere Length
by Will Mannherz and Dr. Suneet Agarwal
Our lab focuses on understanding what controls telomere length from a molecular level, with the hope that this knowledge will help us develop new therapies to treat telomere related diseases. This project began with the simple idea: What if there are pathways in the...
Pharmacologic Rescue of Telomere Defects in Dyskeratosis Congenita
by Dr. Brad Johnson and Dr. Chris Lengner
Telomere disorders including dyskeratosis congenita (DC) manifest in stem cell failure in highly proliferative tissues such as the skin, blood, and gut, as well as fibrosis in organs including lung and liver. While hematopoietic manifestations can be treated with bone...
Pre-malignant Clonal Evolution in Telomere Biology Disorders
by Dr. Daria Babushok, Dr. Bradley Johnson, and Dr. Timothy Olson
We are excited to share an update on our research project, “Pre-malignant Clonal Evolution in Telomere Biology Disorders,” supported by the Team Telomere Million Dollar Bike Ride Grant. Telomere Biology Disorders (TBD) are genetic diseases that cause...
